Biology · Class 12 · Chapter 5

Molecular Basis of Inheritance

13 lessons123 min8 simulations10 practice questions

This chapter looks inside the gene: the structure and packaging of DNA, the experiments that proved DNA is the genetic material, and how information flows by replication, transcription and translation. It ends with the genetic code, gene regulation through the lac operon, the Human Genome Project and DNA fingerprinting, and it underpins the biotechnology chapters that follow.

Also called: molecular biology · DNA replication · transcription and translation · lac operon

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Lessons

13 lessons · 123 min

01The DNA: structure of polynucleotidesNCERT § "The DNA"8 min 02The double helix and central dogmaNCERT § "The DNA"9 min1 sim 03Packaging of the DNA helixNCERT § "The DNA"10 min1 sim 04The search for genetic materialNCERT § "The Search for Genetic Material"10 min1 sim 05Properties of genetic material and the RNA worldNCERT § "The Search for Genetic Material" and § "RNA World"6 min 06ReplicationNCERT § "Replication"14 min2 sims 07TranscriptionNCERT § "Transcription"10 min1 sim 08The genetic code and mutationsNCERT § "Genetic Code"11 min1 sim 09tRNA and translationNCERT § "Genetic Code" and § "Translation"8 min 10Regulation of gene expression: the lac operonNCERT § "Regulation of Gene Expression"10 min1 sim 11Human Genome ProjectNCERT § "Human Genome Project"7 min 12DNA fingerprintingNCERT § "DNA Fingerprinting"7 min 13Chapter reviewMust-know facts, traps and formulas13 min

Simulations

8 in this chapter

Build a DNA double helixIn: The double helix and central dogma Packing 2.2 m of DNA into a nucleusIn: Packaging of the DNA helix Hershey and Chase: is it DNA or protein?In: The search for genetic material Meselson and Stahl: how does DNA copy itself?In: Replication The replication forkIn: Replication Template strand, coding strandIn: Transcription Reading the genetic codeIn: The genetic code and mutations The lac operon switchIn: Regulation of gene expression: the lac operon